Deciphering the chemical language of belowground interkingdom communication and uncovering the underlying mechanisms are major challenges in this field. In recent years, our focus has been on a class of rhizosphere signaling compounds called eclepins, detected in the root exudate of various plant species like potato, tomato, and kidney bean. Initially identified as host cues for parasitic cyst nematodes (CNs) at picomolar concentrations, eclepins were long believed to be solely plant-produced. Surprisingly, we discovered that solanoeclepin A (SolA), found in potato and tomato root exudate, originates from a plant precursor converted to SolA by microbes. Moreover, we have indications that this precursor is a signal in the recruitment of beneficial microbes, particularly under nitrogen deficiency, which strongly boosts eclepin production.
We are looking for a highly qualified and enthusiastic postdoctoral researcher with plant molecular and microbiological expertise to strengthen our team and study the eclepins and their biological significance in microbiome recruitment.
Deciphering the chemical language of belowground interkingdom communication and uncovering the underlying mechanisms are major challenges in this field. In recent years, our focus has been on a class of rhizosphere signaling compounds called eclepins, detected in the root exudate of various plant species like potato, tomato, and kidney bean. Initially identified as host cues for parasitic cyst nematodes (CNs) at picomolar concentrations, eclepins were long believed to be solely plant-produced. Surprisingly, we discovered that solanoeclepin A (SolA), found in potato and tomato root exudate, originates from a plant precursor converted to SolA by microbes. Moreover, we have indications that this precursor is a signal in the recruitment of beneficial microbes, particularly under nitrogen deficiency, which strongly boosts eclepin production.
We are looking for a highly qualified and enthusiastic postdoctoral researcher with plant molecular and microbiological expertise to strengthen our team and study the eclepins and their biological significance in microbiome recruitment.
You will uncover the evolution of the eclepin biosynthetic pathway. Using microbiological approaches and the Microp culture collection from phase I, you will identify the microbes contributing to eclepin formation. By employing knockouts or natural mutants in eclepin biosynthesis, you will demonstrate its role for plant fitness and the modulation of microbial diversity and nematode infection. We anticipate this will further unravel the importance of a new signaling molecule, enriching our understanding of chemical diversification and its impact on the plant-microbiome interaction. The research outcomes hold potential for industry applications, enabling breeders to develop crops with improved microbial relationships and improved N use efficiency. Ultimately, this work may contribute to fertilizer reduction by harnessing beneficial microbes, thereby reducing production costs for farmers and mitigating environmental impacts.
Tasks and responsibilities:
You are passionate about plant metabolism and its role in plant-microbe interactions. You are skilled in biosynthesis and plant molecular biology. You feel comfortable performing data analysis but are also experimentally well-versed. You enjoy working in a multidisciplinary team and are a team player. You have good communication skills as you will be expected to discuss your results with partners and in (inter)national meetings.
Your experience and profile:
You have/are:
We offer a temporary employment contract for 38 hours per week for a period of one year. Upon a good evaluation this will be extended with another 2 years. The preferred starting date is 1 July 2025. The gross monthly salary, based on 38 hours per week and dependent on relevant experience, ranges between € 3,378 to € 5,331 (scale 10). This does not include 8% holiday allowance and 8,3% year-end allowance. The UFO profile Researcher, scale 10 is applicable. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Universities of the Netherlands is applicable.
Are you curious to read more about our extensive package of secondary employment benefits, take a look here.
You will uncover the evolution of the eclepin biosynthetic pathway. Using microbiological approaches and the Microp culture collection from phase I, you will identify the microbes contributing to eclepin formation. By employing knockouts or natural mutants in eclepin biosynthesis, you will demonstrate its role for plant fitness and the modulation of microbial diversity and nematode infection. We anticipate this will further unravel the importance of a new signaling molecule, enriching our understanding of chemical diversification and its impact on the plant-microbiome interaction. The research outcomes hold potential for industry applications, enabling breeders to develop crops with improved microbial relationships and improved N use efficiency. Ultimately, this work may contribute to fertilizer reduction by harnessing beneficial microbes, thereby reducing production costs for farmers and mitigating environmental impacts.
Tasks and responsibilities:
You are passionate about plant metabolism and its role in plant-microbe interactions. You are skilled in biosynthesis and plant molecular biology. You feel comfortable performing data analysis but are also experimentally well-versed. You enjoy working in a multidisciplinary team and are a team player. You have good communication skills as you will be expected to discuss your results with partners and in (inter)national meetings.
Your experience and profile:
You have/are:
We offer a temporary employment contract for 38 hours per week for a period of one year. Upon a good evaluation this will be extended with another 2 years. The preferred starting date is 1 July 2025. The gross monthly salary, based on 38 hours per week and dependent on relevant experience, ranges between € 3,378 to € 5,331 (scale 10). This does not include 8% holiday allowance and 8,3% year-end allowance. The UFO profile Researcher, scale 10 is applicable. A favourable tax agreement, the ‘30% ruling’, may apply to non-Dutch applicants. The Collective Labour Agreement of Universities of the Netherlands is applicable.
Are you curious to read more about our extensive package of secondary employment benefits, take a look here.
The Swammerdam Institute for Life Sciences (SILS) is one of the Faculty of Science’s largest institutes. Its approximately 240 scientists and staff members work in 20 research groups that perform excellent research centered on four themes: Neurosciences, Cell & Systems Biology, Microbiology and Green Life Sciences.
If you enjoy working in an interdisciplinary research team and are eager to contribute to the understanding of how plants interact with other organisms, then the Plant Hormone Biology group is the place to be. We are an international and diverse team of 20+ members, including post-docs, PhD candidates, and technicians with expertise in various scientific areas. We use molecular biology, microbiology, analytical chemistry, and biochemistry to study the crosstalk between organisms and how abundance and function of the root microbiota affect plant performance, including under a range of stresses. Our research is aimed at improving plant performance and resistance and harnessing the potential of beneficial root microbes in crops for sustainable food production with reduced inputs.
The Swammerdam Institute for Life Sciences (SILS) is one of the Faculty of Science’s largest institutes. Its approximately 240 scientists and staff members work in 20 research groups that perform excellent research centered on four themes: Neurosciences, Cell & Systems Biology, Microbiology and Green Life Sciences.
If you enjoy working in an interdisciplinary research team and are eager to contribute to the understanding of how plants interact with other organisms, then the Plant Hormone Biology group is the place to be. We are an international and diverse team of 20+ members, including post-docs, PhD candidates, and technicians with expertise in various scientific areas. We use molecular biology, microbiology, analytical chemistry, and biochemistry to study the crosstalk between organisms and how abundance and function of the root microbiota affect plant performance, including under a range of stresses. Our research is aimed at improving plant performance and resistance and harnessing the potential of beneficial root microbes in crops for sustainable food production with reduced inputs.
If you feel the profile fits you, and you are interested in the job, we look forward to receiving your application. You can apply online via the button below. We accept applications until and including 18 May 2025. Applications should include the following information (all files besides your cv should be submitted in one single pdf file):
A knowledge security check can be part of the selection procedure (for details: National knowledge security guidelines).
Do you have any questions or do you require additional information? Please contact:
If you feel the profile fits you, and you are interested in the job, we look forward to receiving your application. You can apply online via the button below. We accept applications until and including 18 May 2025. Applications should include the following information (all files besides your cv should be submitted in one single pdf file):
A knowledge security check can be part of the selection procedure (for details: National knowledge security guidelines).
Do you have any questions or do you require additional information? Please contact:
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